I am a professor of neurology, chair on cerebrovascular disease and cognition, head of the department general neurology, and project leader of the Vascular Cognitive Impairment (VCI) group of the department of neurology at the UMC Utrecht, the Netherlands.

My research group uses advanced image analysis techniques and high-resolution MRI at 7T to study novel markers of the vascular contribution to cognitive decline and dementia. A typical example is our work on the in vivo detection of cerebral micro infarcts. Cognition and dementia in people with type 2 diabetes (T2DM) is another key topic. We have made important progress in determining the severity and course of development of cognitive dysfunction in T2DM and in identifying underlying MRI correlates. We have recently established a risk score that allows early identification of patients with T2DM at increased risk of cognitive decline and dementia. Our next targets are to further unravel the aetiology and to develop treatment.

I have established several national and international collaborations on VCI related projects, in which we address the above mentioned topics in large patient cohorts. I have supervised 8 completed PhD projects and currently (co)supervise 18 PhD students. I have (co) authored over 160 papers on VCI-related topics.
October 2010 I have started the Utrecht VCI Centre, a multidisciplinary expertise center that offers patients a state of the art diagnosis and treatment and integrates research activities and clinical care.

I have been an active VasCog Participant from the Florence meeting in 2005 onwards, bringing along increasing numbers of PhD students to the meetings over the past years. In 2016, when VasCog will be held in Amsterdam, I will chair the local organizing committee.